There are different kinds of balding conditions that can be influenced by a variety of causes. Stress is perhaps one the leading reasons for hair loss. The other forms such as nutritional deficiency, illness and medication might be a more rare occurrence. The most common out of all these conditions however in androgenic alopecia.
Male pattern baldness is brought about by genetics. Testosterone fuses with the enzyme 5-alpha-reductase to form dihydrotestosterone (DHT). The body uses this to develop and maintain the male reproductive system and is a naturally occurring sequence for every man. DHT however can also cause other things to happen within the body such as hair loss. This is the result of DHT binding with the androgen receptors of the hair follicles. It creates a barrier to the nutrients it receives from the blood supply and slowly causes the hair follicles to shrink. This gradual process in turn, results in the reduction of length and circumference in the hair strands until it disappears entirely. DHT also causes benign prostatic hyperplasia (BPH), a condition where the prostate gland encircling the urethra becomes inflated to the point that it is difficult to urinate.
Creatine is an amino acid used to build muscle and aids in cellular growth. Body builders usually take about 20 grams a day for about 14 days during its loading phase. They then transition into the maintenance phase by ingesting about 5 grams a day for about 2 months or so. Some discontinue its use for a few weeks before resuming to take the same dosage.
Hair loss was observed to result from creatine due to the rise in DHT levels during its use. It was estimated to increase to about 55% during the loading phase and settled to around 40% during the maintenance phase. This is only true however for those who already had high amounts of DHT in their system to begin with. People who had low DHT levels before taking creatine did not exhibit a greater degree of balding. This still requires more actual data however to clearly establish the link between creatine and hair loss. It is only plausible that creatine can cause balding due to the increase in DHT levels upon observation.
It may be of useful consideration to note that DHT needs to successfully bind with the androgen receptors of the hair follicles to induce balding. The bloodstream has to be cut off so that there would be a lack of nutrients supplied to the hair follicles that causes its shrinkage. Increased DHT levels would not matter if the androgen receptors do not attract enough of these hormones to fuse with it. It is this rate of attraction that will dictate how much hair loss will actually take place.
Be that as it may, some creatine users try counteracting any increased hair loss with the use of finasteride. It is only one out the two medications approved by the Food and Drug Administration to treat balding. Finasteride is classified as a 5-alpha-reductase inhibitor, effectively preventing the fusion between it and testosterone leading to a decrease in DHT levels.